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By Dr. Meenu Walia in Medical Oncology , Cancer Care / Oncology , Breast Cancer , Gynecologic Oncology , Thoracic Oncology
Jan 24 , 2025 | 4 min read
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When it comes to cancer treatment, we've come a long way from one-size-fits-all approaches. Today, a powerful new ally in the fight against cancer is immunotherapy. Immunotherapy, rather than attacking the disease directly, empowers your body’s immune system to recognize and fight cancer cells more effectively.
What Makes Immunotherapy So Different?
Unlike chemotherapy or radiation, which aim to destroy cancer cells with chemicals or high-energy waves (sometimes harming healthy cells in the process), immunotherapy works with your body, not against it. Think of it as unlocking your immune system’s full potential—helping it detect and destroy cancer cells that usually manage to hide in plain sight.
Cancer is sneaky. It often tricks the immune system into thinking it’s not a threat. But immunotherapy steps in and removes those disguises, allowing your immune defenses to do their job more efficiently.
How the Immune System Becomes a Cancer Warrior
Your immune system is built to fight invaders like viruses and bacteria. But when it comes to cancer, the signals get confusing. Some cancer cells mimic normal cells or suppress immune responses altogether.
Immunotherapy retrains the immune system. It’s like giving your immune soldiers better training, smarter weapons, and sharper vision—helping them identify and target cancer more precisely. Some approaches help “wake up” sleepy immune cells, while others block cancer’s ability to shut the immune system down.
Why It’s a Game-Changer in Modern Oncology
Personalisation is immunotherapy's real ability. It's not about giving the same treatment to every patient—it’s about tailoring it based on your specific cancer type, how your immune system responds, and even your genetics.
Here’s why it stands out:
- Fewer Side Effects: It tends to spare healthy cells, so many people experience less fatigue, nausea, or hair loss compared to chemo or radiation.
- Long-Term Protection: Some immunotherapies leave behind “immune memory,” meaning your body may remember how to fight that specific cancer if it returns.
- Precision-Focused: Instead of general destruction, it’s a guided attack. Immunotherapy pinpoints what needs to be destroyed and leaves the rest untouched.
- Hope for Hard-to-Treat Cancers: Immunotherapy has shown surprising success for some cancers that don’t respond well to traditional methods.
Emerging Breakthroughs to Watch
The world of advanced cancer treatment is evolving fast. Immunotherapy is no longer limited to a few types of cancer. Research is expanding its use across more forms of the disease, and combinations with other treatments are proving even more powerful.
Tumour-specific vaccines are also being explored—not to prevent cancer but to help treat it by targeting cancer cells directly. These vaccines stimulate the immune system to target unique markers on cancer cells. Other breakthroughs include gene-based immune boosters, which may one day allow doctors to design treatments based on an individual's immune profile.
What Should Patients Know Before Considering Immunotherapy?
While immunotherapy sounds promising, it’s not suitable for everyone. Here’s what to keep in mind:
- It Works Differently for Everyone: Some people respond dramatically, while others may see gradual changes. Your doctor might need to monitor your progress closely and adjust your plan over time.
- It May Take Time: Unlike chemotherapy, which often causes immediate changes, immunotherapy can take longer to show results. Patience is key.
- There Can Be Side Effects: While generally milder, side effects like fatigue, rashes, or inflammation may occur. These usually happen when the immune system becomes too active.
- Not All Hospitals Offer It: Since it’s a specialised treatment, it's important to find a centre with experience in personalised cancer care and immunotherapy-based approaches.
Common Misconceptions
Let’s bust a few myths:
- “It’s only for late-stage cancer.”
Not true. It’s also being studied for early-stage cancers, especially when used alongside other modern treatments.
- “It always replaces chemo or radiation.”
Actually, in many cases, it’s used in combination with other therapies for better outcomes.
- “It guarantees a cure.”
While it offers hope and extended survival for many, it’s not a magic bullet. But it’s certainly a powerful tool in the evolving fight against cancer.
Conclusion
Immunotherapy is a revolutionary shift in how we think about treating cancer. Tapping into the body’s own defence system opens up possibilities for targeted, long-lasting, and less toxic treatments. And as science continues to evolve, we can expect even more exciting developments in the world of personalised oncology.
If you or a loved one is exploring treatment options, talk to your doctor about whether immunotherapy might be a good fit. Personalised cancer care isn’t just the future—it’s happening now.
Frequently Asked Questions
Can immunotherapy be used alongside traditional treatments like surgery or radiation?
Yes, in many cases, it’s part of a combination plan. Immunotherapy may be given before or after other treatments to improve outcomes.
What happens if immunotherapy stops working?
Doctors may switch strategies or combine them with another therapy. The immune system evolves, and so does the treatment approach.
Does everyone have access to immunotherapy?
Access depends on the type and stage of cancer, hospital facilities, and treatment availability. A second opinion may help explore more options.
Is monitoring during immunotherapy different from chemotherapy?
Yes, doctors often use scans and immune markers to assess progress, which can look different from tumour shrinkage seen in chemo.
How is success measured in immunotherapy if results take time?
Beyond tumour size, doctors look at how long the response lasts, how stable the disease stays, and how well the immune system remains active.

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