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Blood Clot in Brain: Types, Causes and Treatment

By Dr. Kapil Jain in Neurosciences

Feb 24 , 2025 | 7 min read

Blood clots, which are typically the body’s natural response in the healing process (to prevent bleeding), can become dangerous when they form inside blood vessels and obstruct blood flow. A blood clot in the brain occurs when a blood vessel becomes blocked or ruptures, disrupting the flow of oxygen and nutrients to the brain. This can lead to severe complications, including damage to brain cells, strokes, or even death. While some individuals may experience mild episodes without noticeable symptoms, others may face serious complications like seizures or paralysis. Understanding the risks and symptoms of blood clots is essential for ensuring prompt medical attention. If you notice any concerning signs, consult a healthcare professional immediately to seek appropriate treatment.

Types of Blood Clots

There are two types of blood clots: Thrombosis and Embolism. Let’s explore these types in detail and understand the causes and treatment options for blood clots in the brain.

1. Thrombosis 

Thrombosis is the formation of a blood clot within a blood vessel when it becomes damaged and filled with blood. This can result from trauma or other medical conditions. These blood clots are stationary and remain at the site where they are formed.

2. Embolism

Embolism, on the other hand, occurs when an artery is blocked by a foreign object, such as a blood clot, clotting material, or even tissue. These blood clots often travel from their original location to another part of the body, such as the brain, where they can cause a blockage.

Symptoms of a Blood Clot in the Brain

A blood clot in the brain can disrupt the flow of oxygen and nutrients, leading to serious and sometimes life-threatening symptoms. Recognizing these signs early can help in seeking timely medical intervention. Given below are the symptoms you should watch out for:

  • Intense and Recurring Headaches: Persistent headaches that don’t subside with rest can be a warning sign. Even if you’re physically inactive, you may still feel pain and discomfort in your head. Sudden headaches accompanied by pressure in the head or numbness in the face and body could indicate a blood clot in the brain.
  • Speech Difficulties, Such as Slurring: A blood clot can starve the brain of oxygen, leading to damage that affects speech. You might notice slower or slurred speech, making it difficult to communicate clearly. Such impediments can be an early indication of a blood clot in the brain.
  • Blurry Vision: Blurred vision is another early symptom. Oxygen deprivation in the brain can interfere with normal visual processing, causing your surroundings to appear hazy or fuzzy.
  • Uncontrollable Motor Functions: As the brain sustains more damage, you might experience uncontrollable movements, such as shaking or tremors. These can start mildly but may intensify as the blockage worsens.
  • Seizures: A growing blood clot can trigger seizures. While these seizures may be brief, they can also become prolonged and severe in some cases.
  • Dizziness: Oxygen deprivation in the brain can lead to dizziness or lightheadedness. In more extreme cases, people might even experience fainting episodes.
  • Paralysis: As the blood clot enlarges, it can cause paralysis. Depending on the clot’s location in the brain, this paralysis might affect specific parts of the body or lead to more widespread immobility.

What are the Causes of Blood Clot Formation in the Brain?

Several factors can contribute to the formation of blood clots in the brain. Below are some common causes:

  • Obesity: Obesity is one of the primary risk factors for blood clots in the brain. Fat cells are more prone to clotting, and having a high body mass index (BMI) significantly increases the risk. Excess weight can also lead to other health issues that exacerbate clot formation.
  • Smoking: Smoking damages blood vessels and is a major cause of blood clots. It lowers the levels of nitrogen oxide (NO) in the blood, impairing its ability to flow smoothly. Smoking can also lead to conditions such as thrombosis and embolism, increasing the likelihood of high blood pressure and blood clots.
  • Birth Control Pills: Certain birth control pills can elevate the risk of blood clots in the brain. These medications often affect estrogen levels, which can increase the likelihood of clot formation, especially in individuals with other risk factors.
  • Brain Trauma: Research suggests that trauma to the brain can result in blood clots. Head injuries often cause internal bleeding, which may lead to clot formation as the body tries to heal the damaged blood vessels.
  • Atherosclerosis: Atherosclerosis occurs when arteries harden due to the buildup of fat, calcium, and other substances, collectively known as plaque. When these plaques become disrupted, platelets can accumulate at the site of damage, forming clots. This process can obstruct blood flow to the brain, increasing the risk of clot-related complications.

Diagnosis of a Blood Clot in the Brain

Diagnosing a blood clot in the brain requires a combination of tests to determine its presence, location, and severity. Early and accurate diagnosis is critical to prevent serious complications. Below are the common methods used for diagnosis:

Blood Tests

Doctors may perform blood tests to check for specific markers indicating a blood clot. For instance, the presence of certain proteins in the bloodstream could signal bleeding or clotting in the brain.

Ultrasound

An ultrasound scan may be used to examine the size and shape of the brain and its blood vessels. It can provide insight into the possible location of the clot and help trace its origin.

CT Scan

CT scans are a highly accurate imaging technique to detect blood clots in the brain. They provide detailed images that can reveal the nature and extent of the clot, making it easier to plan appropriate treatment.

Magnetic Resonance Angiography (MRA)

MRA is a specialised imaging test used to visualise blood vessels in detail. It can identify blockages, abnormalities, and disruptions in blood flow within the brain, as well as locate the source of the clot.

V/Q Scans

Ventilation-perfusion (V/Q) scans help measure oxygen levels in the blood and assess both arterial and venous blood flow. They can also identify any blockages or clotting in the blood vessels that might be causing reduced oxygen supply to the brain.

Treatment of Blood Clots in the Brain

Timely and effective treatment of blood clots in the brain is crucial to prevent further complications, such as stroke or permanent brain damage. The choice of treatment depends on the size, location, and severity of the clot, as well as the patient’s overall health. Below are the common treatment methods:

Anticoagulant Medications

This treatment involves using medications that thin the blood to prevent further clotting. Anticoagulants and antiplatelets, such as warfarin, are often prescribed for individuals with a history of blood clots or those who have had a stroke caused by a clot. These medications help reduce the risk of additional clots forming.

Thrombolytics

Thrombolytics are powerful drugs designed to rapidly dissolve blood clots. They are typically administered in emergency cases, such as strokes caused by a blood clot. For example, heparin is a commonly used thrombolytic in such situations.

Mechanical Thrombectomy

This is a surgical procedure used to physically remove blood clots from the brain. A specialised device equipped with a mesh is inserted into the main artery to extract the clot, restoring proper blood flow to the brain.

Surgery for Blood Clots in the Brain

Surgery may be recommended to remove blood clots and relieve pressure on the brain. Common surgical options include:

  • Burr Hole Drainage: A small hole is made in the skull to drain the blood clot, alleviating pressure on the brain.
  • Craniotomy: A section of the skull is temporarily removed to access and remove the clot, after which the skull piece is replaced.

Stenting

Stents are small tubes inserted into the brain’s blood vessels to keep them open. This ensures proper blood flow and reduces the risk of further blockages.

Vena Cava Filters

Vena cava filters are small devices placed in the inferior vena cava (a large vein) to catch blood clots before they travel to critical areas such as the brain, heart, or lungs. These filters are inserted using an endoscope or catheter, offering a minimally invasive solution.

Conclusion

The symptoms of a blood clot in the brain can range from mild issues, such as slurred speech, to severe complications, including strokes that lead to paralysis. Recognising these signs early is crucial for prompt diagnosis and treatment. If you experience any of these symptoms, it is essential to consult a doctor at a reputable hospital, such as Max, without delay to receive appropriate care and treatment.

Frequently Asked Questions About Blood Clots in the Brain

1. How to remove a blood clot in the brain without surgery?

Non-surgical methods to treat blood clots in the brain include medications such as anticoagulants (blood thinners) and thrombolytics, which help dissolve clots and prevent new ones from forming. These treatments are often used in less severe cases or as an initial response.

2. What is the best treatment for a blood clot in the brain?

The best treatment depends on the clot's severity, location, and underlying causes. Options include anticoagulants, thrombolytics, mechanical thrombectomy, and in some cases, surgery. Consulting a specialist is essential for determining the most effective treatment plan.

3. Is a blood clot in the brain dangerous?

Yes, a blood clot in the brain is a serious medical condition. It can block oxygen and nutrient supply, potentially causing strokes, brain damage, or even death if not treated promptly.

4. Can you fully recover from a blood clot in the brain?

Recovery depends on the size and location of the clot, as well as how quickly treatment is received. Many people recover fully, especially with early diagnosis and appropriate treatment. However, some may experience long-term complications.

5. What are the chances of surviving a brain blood clot?

Survival rates vary based on the severity of the clot and the speed of medical intervention. Early treatment significantly improves the chances of survival and reduces the risk of complications.