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Month Red Autoclave(Infected Plastic Waste) Yellow- Incineration(AnatomicalWaste & Soiled Waste) Blue Autoclave (Glass- Bottles) Black Cytotoxic- Incineration( Cytotoxic Contaminated Items) White- Sharp Total Bags Total Weight(In KG's)
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Jun-17 1060 4511.45 902 2886.66 293 1324.05 76 194.00 2057 1100.69 4388 10016.85
Jul-17                     0 0.00
Aug-17                     0 0.00
Sep-17                     0 0.00
Oct-17                     0 0.00
Nov-17                     0 0.00
Dec-17                     0 0.00
Jan-18                     0 0.00
Feb-18                     0 0.00
Mar-18                     0 0.00
YTD 3159 12099.065 2884 9379.155 808 3865.69 266 668.705 5505 2530.94 12622 28543.555

CAR T Cell therapy

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January 7, 2019 0 1 minute, 9 seconds read
Dr Gaurav Dixit - Max Hospital
Consultant - Haematology & Bone Marrow Transplant
Cancer Care / Oncology, Bone Marrow Transplant, Haematology, Medical Oncology

Cancer can be a devastating diagnosis for anyone, especially when it strikes young children. B cell lymphoblastic Leukemia (ALL), is a type of blood cancer, which is very common in the younger age group. Treatment of ALL  has come a long way. From single-agent methotrexate chemotherapy in the 1940s to multi-agent chemotherapy regimens, treatment for this disease has undergone a sea change. Survivals have also increased significantly. Now in 2018, we talk about cure rates of 70-80% as compared to few months survival about 4-5 decades back. 

Challenge now is about 20-30% patients who have relapse refractory disease. CAR T cell therapy is a type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells.  In the first step, T cells are taken from patient’s blood. Then the gene for a special receptor that binds to a certain protein on the patient’s cancer cells is added in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion.

CAR T cells are very effective in treating relapsed and refractory B ALL patients. Efforts are going on to develop these cells in India to bring down the cost. Presently this therapy has FDA approval for ALL and lymphomas.

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