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By Dr. Gyanendra Agrawal in Pulmonology
Jun 04 , 2025 | 9 min read
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After disrupting the world for more than 2 years, coronavirus seems to be resurfacing in new variants such as LF.7 and NB.1.8.1. While the names may sound unfamiliar, these are simply new variants of the virus. Some parts of India have seen a rise in cases linked to these sub-variants, prompting questions about symptoms, safety, and what actions to take. The good news is that most infections reported so far were mild, and the same preventive steps used during earlier COVID-19 waves, such as masking, hand hygiene, social distancing and vaccination, still offer strong protection. At the end of the day, staying informed is the key to staying safe.
Understanding the LF.7 and NB.1.8.1 Variants
LF.7 and NB.1.8.1 are new variants of the coronavirus, mutated from the Omicron variant: a version of the virus known for spreading easily but usually causing milder illness. These variants have gained attention due to a noticeable rise in infections in certain regions, particularly across parts of India and the United States.
NB.1.8.1 is a subvariant of the BA.2.86 lineage (closely linked to JN.1), while LF.7 is part of a separate Omicron branch. Both are characterised by mutations in the spike protein, which may influence their transmissibility and immune evasion potential. Although there is no conclusive evidence yet suggesting that these variants cause more severe illness, their ability to spread rapidly has made them a focus of genomic surveillance.
Health experts are closely monitoring how these variants behave compared to previous strains. While they do not represent an entirely new wave, their emergence underscores the importance of continued vigilance, testing, and appropriate precautions.
Current COVID Variant Trends in India
India has witnessed a gradual uptick in COVID-19 cases attributed to newer Omicron sub-lineages such as NB.1.8.1 and LF.7. These variants have been detected through routine genomic surveillance conducted by INSACOG (Indian SARS-CoV-2 Genomics Consortium), which monitors mutations and assesses their public health impact.
Recent reports suggest isolated clusters in states including Maharashtra, Kerala, Gujarat, and Delhi, although no major nationwide surge has been reported so far. The overall case numbers remain lower than previous waves, but localised increases and community transmission are being closely watched by health officials.
International travel, crowded indoor gatherings, and reduced masking in public spaces may be contributing to the spread. While hospitalisation rates have not shown a significant spike, the presence of these sub-variants underscores the need for continued vigilance, especially among the elderly and immunocompromised.
Symptoms to Watch For
The symptoms of LF.7 and NB.1.8.1 are mostly similar to earlier Omicron sub-variants. In most cases, the illness is mild and resembles a seasonal flu or cold, especially in vaccinated individuals.
Common Symptoms
- Fever: Often low-grade and persistent.
- Cough: Dry or with phlegm.
- Sore Throat: Irritation or pain in the throat.
- Runny or Stuffy Nose: Nasal congestion or discharge.
- Fatigue: General tiredness or lack of energy.
- Headache: Mild to moderate intensity.
- Muscle or Body Aches: Generalized discomfort or pain.
Some people may also experience changes in smell or taste, though this is now less common. Symptoms usually last a few days and improve with rest and hydration.
Who’s at Risk
While most people recover quickly, certain groups may be more vulnerable to complications from these variants.
People at Higher Risk
- Older adults, especially over the age of 60
- Individuals with chronic conditions such as diabetes, heart disease, or lung problems
- People with weakened immune systems (due to cancer, medications, or other illnesses)
- Those who are unvaccinated or overdue for a booster dose
For these individuals, even a mild infection can sometimes lead to more serious health issues. That’s why extra precautions and early medical attention are important.
How These Variants Spread
The LF.7 and NB.1.8.1 variants spread the same way as other COVID-19 variants, which is mainly through the air when an infected person coughs, sneezes, talks, or even breathes in close contact with others. These sub-variants are believed to be highly contagious, which means they can spread quickly, especially in crowded or poorly ventilated places such as:
- Public transport and stations
- Markets and shopping malls
- Offices and classrooms
- Social gatherings and events
Note: Touching surfaces and then touching the nose, mouth, or eyes can also pose a small risk, although this is less common. People who don’t have symptoms (asymptomatic carriers) can still pass the virus to others.
Are LF.7 and NB.1.8.1 More Dangerous Than Covid-19 Strains?
So far, there is no strong evidence that the LF.7 and NB.1.8.1 variants are more dangerous than previous COVID-19 strains. Most people infected with these variants have shown mild to moderate symptoms, especially if they are vaccinated or have had COVID before.
However, doctors are still studying these variants to see if they:
- Spread faster than older variants
- Cause more serious illness in high-risk people
- Evade immunity from vaccines or past infections
Health experts are particularly watchful about how these variants behave in people with weak immune systems, such as the elderly or those with existing health conditions. These groups may still be at risk for complications, even with a mild variant.
In short, while these new variants are not currently linked to higher severity, their fast spread and ability to infect people again (reinfection) make them important to monitor.
Prevention and Safety Measures
Even with new variants like LF.7 and NB.1.8.1, the ways to protect yourself and others remain the same, and they still work well. Following basic precautions can greatly reduce the risk of infection, especially in crowded or high-risk areas.
Here are key safety measures to follow:
- Wear a mask in public places, and crowded areas
- Wash hands often with soap and water or use hand sanitiser
- Avoid close contact with people showing cold or flu-like symptoms
- Keep windows open or stay in well-ventilated spaces when indoors
- Cover coughs and sneezes with a tissue or elbow
- Stay home if unwell to prevent spreading illness to others
- Maintain distance in public places whenever possible
- Keep up with vaccination and booster doses as advised by your doctor
These steps not only help protect against COVID-19 but also reduce the spread of other seasonal infections.
Testing, Isolation, and When to Seek Medical Help
If you feel unwell or have symptoms such as fever, cough, or sore throat, it’s important to get tested. Early diagnosis helps stop the spread and ensures timely care.
When to Get Tested
- If you have COVID-like symptoms
- After contact with someone who tested positive
- If oxygen saturation is <94%
RT-PCR tests remain the most reliable way to confirm infection. Rapid antigen tests can give quicker results but may need confirmation.
What to Do if You Test Positive
- Isolate at home in a separate, well-ventilated room
- Wear a mask when around others
- Stay hydrated and rest
- Monitor symptoms regularly, especially oxygen levels if possible
- Inform close contacts so they can also take precautions
Seek Medical Help If You Notice
- Difficulty breathing
- Chest pain or pressure
- High fever that doesn’t come down
- Sudden confusion or severe weakness
People with health conditions such as diabetes, heart disease, or low immunity should consult a doctor early, even for mild symptoms.
How Max Healthcare is Responding
Max Hospital continues to stay prepared as new COVID-19 variants such as LF.7 and NB.1.8.1 emerge. Our hospitals follow strict infection control measures and are equipped to handle COVID-19 cases with safety, accuracy, and speed.
Here’s how Max Healthcare supports patients:
- RT-PCR and advanced testing facilities for early and reliable detection
- Dedicated fever clinics and isolation wards for safe care delivery
- Vaccination and booster support based on the latest government guidelines
- Expert consultations through in-person and online appointments
- Trained medical teams for COVID monitoring, symptom management, and recovery planning
- Home care options including teleconsultation and medicine delivery for mild cases
Whether it’s early diagnosis, guidance during recovery, or preventive care, Max Healthcare is committed to providing trusted support every step of the way.
Daily Life Tips for Staying Safe During New Variant Surges
With new COVID-19 variants spreading, it’s helpful to make a few small changes to daily habits to stay safe, especially in public or shared spaces.
Simple tips to follow:
- Limit unnecessary travel or outings during local surges
- Carry a mask and hand sanitiser whenever stepping out
- Avoid touching your face in public areas
- Disinfect frequently used items like phones, wallets, and doorknobs
- Eat a balanced diet with fruits, vegetables, and immunity-boosting foods
- Get enough sleep and manage stress to keep your immune system strong
- Avoid panic, but stay informed from reliable sources
- Check in on elders and those with health conditions to ensure they are following precautions
These habits are easy to follow and can go a long way in reducing risk for you and others, especially during unpredictable variant waves.
Book a Consultation or COVID Test at Max Healthcare
Early detection and expert guidance can make all the difference when it comes to managing new COVID-19 variants. Whether it’s getting tested, speaking to a doctor, or accessing home care, Max Healthcare offers safe and accessible options tailored to individual needs. From RT-PCR testing and booster support to COVID consultations and post-recovery care, Max hospitals are equipped to support every stage of prevention and treatment.
To book a COVID-19 test or consult a specialist at Max Healthcare, call 88604 44886 or visit the official Max Hospital website to schedule your appointment online.
Frequently Asked Questions
Are NB.1.8.1 and LF.7 more dangerous than earlier COVID-19 variants?
Current data suggests that these variants are not more dangerous in terms of severity, but they may spread more easily. Most cases continue to be mild, especially in vaccinated individuals.
Do these variants lead to more severe illness or complications?
So far, the majority of infections with NB.1.8.1 and LF.7 have been mild to moderate. However, people with underlying health conditions should remain cautious, as they may still face a higher risk of complications.
How are new COVID-19 variants like NB.1.8.1 and LF.7 monitored or classified as concerning?
Health authorities assess new variants based on their rate of spread, impact on hospitalisations, response to vaccines, and ability to cause reinfections. Variants showing significant change are closely monitored by global and national agencies such as WHO and INSACOG.
Is NB.1.8.1 responsible for the rise in COVID-19 cases in India?
NB.1.8.1 has been detected in several Indian states and may be contributing to localised increases. However, case numbers remain relatively low, and multiple factors can influence case surges.
Do COVID-19 booster shots still offer protection against these variants?
Yes. Boosters help strengthen the immune response and reduce the risk of severe illness, even if the virus mutates. Updated vaccines are designed to offer broader protection across variants.
Are children more vulnerable to NB.1.8.1 and LF.7?
There is no evidence that these variants specifically target children more than others. However, children with pre-existing medical conditions should continue to follow precautions and stay up to date with vaccinations.
Is hospitalisation increasing because of these new variants?
At present, hospitalisation rates remain stable and manageable. Most individuals recover at home with basic care, although vulnerable populations may require closer monitoring.
How can I get tested to know if I’ve been infected with one of these variants?
Standard RT-PCR tests can confirm a COVID-19 infection. To identify the specific variant, samples are selected for genome sequencing, which is handled by designated labs as part of public health surveillance.
Does NB.1.8.1 spread faster than other variants?
Preliminary reports suggest that NB.1.8.1 may have a higher transmission rate, similar to previous Omicron sub-lineages. This makes following preventive measures even more important.
What is India doing to track and manage these new variants?
The Indian government, through INSACOG, is regularly conducting genome sequencing to monitor new variants. Health advisories are updated based on findings, and state-level containment strategies are in place.
What extra precautions should be taken during a new variant surge?
Stick to proven safety practices such as masking in crowded areas, hand hygiene, maintaining distance, avoiding poorly ventilated spaces, and staying updated with booster doses.

Written and Verified by:
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