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What Causes Swollen Lymph Nodes

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Swollen Lymph Nodes: Common Causes and Ways to Reduce Swelling

By Dr. Monica Mahajan in Internal Medicine

May 30 , 2025 | 3 min read

Swollen lymph nodes, medically called lymphadenopathy, are a common sign that the body is responding to an infection or another underlying condition. When lymph nodes swell, it usually means they are working harder than usual to trap viruses, bacteria, or other invaders. In most cases, swollen lymph nodes are not a cause for alarm and tend to improve once the underlying issue is treated. However, sometimes they can signal a more serious health problem that needs medical attention.

In this blog, we will look at some of the most common causes of swollen lymph nodes and explore ways to help reduce the swelling effectively—starting with an overview of lymph nodes and their role.

What are Lymph Nodes?

Lymph nodes are small, bean-shaped glands that form part of the lymphatic system—a network that helps the body fight infections and maintain fluid balance. They act as filters, trapping viruses, bacteria, and other harmful substances before they can spread to other parts of the body. Lymph nodes contain white blood cells, which work to destroy these unwanted invaders.

They are found in groups throughout the body, most commonly in the neck, armpits, chest, abdomen, and groin. Under normal conditions, lymph nodes are usually not noticeable. However, they can become swollen and tender when the body is fighting an infection or dealing with another health issue.

What Causes Swollen Lymph Nodes?

Swollen lymph nodes often occur when the body responds to infections or other underlying conditions. Several factors can lead to this swelling:

Infections

The most common cause:

  • Viral Infections: Colds, flu, measles, and mononucleosis can lead to swelling, which usually resolves as the infection clears.
  • Bacterial Infections: Strep throat, ear infections, or skin infections can cause nearby lymph nodes to swell and become tender.
  • Other Infections: Fungal or parasitic infections like toxoplasmosis are less common but can also cause swelling.

Immune System Disorders

Autoimmune conditions can trigger lymph node swelling:

  • Rheumatoid Arthritis: Can lead to generalised lymph node enlargement.
  • Lupus: Causes inflammation throughout the body, including the lymph nodes.

Cancer

Less commonly, persistent or painless swelling may indicate:

  • Lymphoma: Cancer starting in the lymphatic system.
  • Leukaemia: Abnormal white blood cells accumulating in the nodes.
  • Metastatic Cancer: Spread from other body parts like the breast or lungs.

Other Causes

  • Medications: Certain drugs, including anti-seizure medications.
  • Vaccinations: Temporary swelling, especially under the arm post-vaccine.
  • Injury/Inflammation: Trauma or localised inflammation can lead to swelling.

When to Be Concerned About Swollen Lymph Nodes

While most cases are harmless and resolve with time, you should consult a doctor if you notice:

  • Swelling lasting longer than a few weeks
  • Lymph nodes larger than 2.5 cm
  • Hard, fixed, or painless lymph nodes
  • Accompanying symptoms like:
    • Fever or night sweats
    • Unexplained weight loss
    • Persistent fatigue
    • Red, warm, or painful skin over the node

Diagnosing the Cause of Swollen Lymph Nodes

  • Physical Examination: Doctors examine the size, tenderness, and location of the nodes.
  • Blood Tests: To detect infections, immune disorders, or signs of systemic inflammation.
  • Imaging Tests: Ultrasounds or CT scans help visualise internal lymph nodes and surrounding tissue.
  • Biopsy: If cancer is suspected, a tissue sample may be examined for abnormal cells.

Natural Ways to Reduce Lymph Node Swelling

While medical treatment focuses on the root cause, these home remedies may provide symptom relief:

  • Warm Compresses: Increases blood flow, reduces inflammation.
  • Rest and Hydration: Helps the body recover and flush out toxins.
  • OTC Pain Relievers: Ibuprofen or acetaminophen can ease pain and swelling.
  • Gentle Massage: Lightly massaging the area may help drain lymphatic fluid.
  • Anti-Inflammatory Diet: Include turmeric, ginger, garlic, and leafy greens.
  • Elevation: Supports drainage if swelling is in a limb or accessible area.

Medical Treatments for Swollen Lymph Nodes

Based on the underlying cause:

  • Bacterial Infections: Treated with antibiotics.
  • Viral Infections: Symptomatic relief through rest, fluids, and OTC meds.
  • Autoimmune Diseases: Managed with immunosuppressive medications.
  • Cancer: May require chemotherapy, radiation, or surgery.
  • Pain Management: Warm compresses or medication can ease discomfort.

Consult a Doctor

If you’re experiencing persistent or unexplained swollen lymph nodes, don’t wait. Schedule an appointment with your healthcare provider to get a proper diagnosis and the right treatment.

Conclusion

Swollen lymph nodes are usually a sign that your immune system is doing its job. Most cases resolve without medical intervention, especially those caused by minor infections. However, if the swelling persists, worsens, or is accompanied by other concerning symptoms, it's important to seek medical advice. Early diagnosis and treatment can be critical, especially if the swelling is related to a more serious condition like cancer or an autoimmune disease.


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