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Liver Transplant and Biliary Sciences

Liver Transplant and Biliary Sciences

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Overview

In liver transplant surgery, the patient’s old liver is removed completely and a new one from a liver donor is put in the same place after joining the blood vessels and the bile duct. The donor liver can be from a dead person where usually the whole liver is transplanted or more commonly it is from a family member who donates part of his or her liver. Although we only have one liver in our body, liver can now be safely divided in to 2 parts so that one part can be taken out for transplantation and the remaining liver is sufficient for the donor. Both these portions can regenerate quickly to its original size though the shape will become different. Liver transplant is reserved for those whose liver disease has progressed so much that their general condition is critical. Generally, these are patients who have exhausted other forms of treatment or side by side have developed liver cancer. In cadaveric transplant, the wait can be unpredictable and some patients will die while waiting for a donor liver. On the other hand, living donor liver transplant can be done when the patient really needs it and when the entire team is available as it is a planned operation.

Max Centre for Liver Transplant and Biliary Sciences is one the busiest and a very popular destination for liver transplantation in India. Many patients from overseas chose to come here for their treatment as the outcomes has been phenomenally successful. This has been possible because the Centre has experienced doctors and the entire team has established in liver transplantation in India way back in 2001. A team of 200 members with 20 years of experience have done 2600 plus transplants and this team is now based in Max Centre for Liver and Biliary Sciences at Max Super Specialty Hospital, Saket & Vaishali. Max hospital ensures that the patient receives the intense care during and after the surgery. Currently, the success rate of Liver transplant is over 95% and ten year survival is over 80%.

Liver failure can occur rapidly, in a matter of weeks (acute liver failure), or it can occur slowly over months and years (chronic liver failure). There are different causes for liver failure such as chronic viral infection with B and C virus, liver tumor, alcoholism, fatty liver, bile duct abnormalities (primary biliary cholangitis, primary sclerosing cholangitis and biliary duct atresia). Hepatitis B and C are the two most common infections across the world. Luckily there is an effective vaccine for hepatitis B and cure by drugs for hepatitis C. Primary Liver Cancer develops in chronically diseased livers and sometimes develops rapidly so that no treatment is possible. If picked up on screening when the size is small, liver transplant can cure these patients.

Across the globe most potential recipients are curious to know how life will be after transplant. In brief the life is exactly the same as before with minor restrictions such eating hygienically prepared food, live in clean surroundings and do regular tests as advised by the doctor and comply with immunosuppressive medications.

Liver Transplant and Biliary Sciences: Condition & Treatments

Acute Liver Failure (ALF)

Acute liver failure occurs when your liver rapidly loses its ability to function. More commonly, liver failure develops slowly over the course of years. But in acute liver failure, liver failure develops in a matter of days.

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Alcoholic Liver Disease

Alcohol is the most widely abused agent in the world and its excessive intake is the leading cause of liver disease. It is consumed as beer, wine or distilled spirit and a blood level of 100 mg/dl is the legal definition for drunk driving in India. A blood concentration of 200 mg/dl causes inebriation while a level of 300-400 mg/dl can lead to coma, respiratory arrest and death.

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Hepatitis A

Hepatitis A is a viral liver disease that can cause mild to severe illness. It relates to inflammation (irritation and swelling) of the liver.The hepatitis A virus is transmitted through ingestion of contaminated food and water, or through direct contact with an infectious person. The hepatitis A virus is one of the most frequent causes of food borne infection. Epidemics related to contaminated food or water can erupt explosively, such as the epidemic in Shanghai in 1988 that affected about 300 000 people. Hepatitis A viruses persist in the environment and can resist food-production processes routinely used to inactivate and/or control bacterial pathogens. Improved sanitation and the hepatitis A vaccine are the most effective ways to combat the disease.

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Hepatitis B

Hepatitis B is the most common liver infection in the world and is caused by the hepatitis B virus. The hepatitis B virus enters the body and travels through the blood to the liver. In the liver, it attaches to the liver cells and multiplies. Although the patient may not have any problems at this phase, multiplication of the virus triggers a response from the body’s immune system. Hepatitis B infection can lead to cirrhosis (scarring of the liver), liver failure or even liver cancer unless diagnosed and managed early. There are probably 350-400 million people with chronic (lifelong) hepatitis B infection worldwide. Hepatitis B infection is considered to be ’acute‘ in the first 6 months after infection. If hepatitis B virus tests (HBsAg) are positive after 6 months, this is now a ‘chronic’ (long term) hepatitis B infection, which may last a lifetime.

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Hepatitis C

Hepatitis C is spread by direct blood-to-blood contact. For this reason, it is difficult to get or give hepatitis C unless there is blood transfusion involved.

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Liver Cirrhosis (CLD)

Cirrhosis of the liver is a slowly progressing disease in which healthy liver tissue is replaced with scar tissue, eventually preventing the liver from functioning properly. The scar tissue blocks the flow of blood through the liver and slows the processing of nutrients, hormones, drugs, and naturally produced toxins. It also slows the production of proteins and other substances made by the liver.

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Liver Tumour Cancer

Liver cancer, also known as hepatocellular cancer, is cancer that originates in the liver itself. If cancer develops in another part of the body and spreads to the liver, it is known as liver metastases. Tumours that originate in the colon, lung, breast, pancreas, stomach, and other organs and spread to the liver through the bloodstream can also give rise to liver cancer.

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Our Medical Experts

Max Healthcare is home to 4800+ eminent doctors in the world, most of whom are pioneers in their respective fields. Additionally, they are renowned for developing innovative and revolutionary clinical procedures.

Our Medical Experts

Max Healthcare is home to 4800+ eminent doctors in the world, most of whom are pioneers in their respective fields. Additionally, they are renowned for developing innovative and revolutionary clinical procedures.

Find a Doctor
Find a Doctor

Our Technological Advancements

CUSA Machine

Sonopet Ultrasonic Aspirator Delivers precise fragmentation Longitudinal Torsional Technology Bone/hard tissue dissection Capable of running hand pieces at multiple frequencies Includes onboard suction and irrigation systems

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CT Scan

GE Lightspeed 16-slice CT scanner Xtream FX suite workflow management Full Dicom connectivity Auto-segmentation 70cm gantry opening 65cm variable field of view High 2D and 3D resolution

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Real Patients, Real Stories.

Liver Transplant Surgery for Autoimmune Liver Disease | Patient Success Story

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

Nov 14, 2022

Liver Transplant Surgery for Liver Cirrhosis Treatment

Treated by Dr. Shaleen Aggarwal, Max Super Speciality Hospital, Saket

Sep 14, 2022

Liver Transplant Surgery for Polycystic Liver Disease

Treated by Dr. Shaleen Aggarwal, Max Super Speciality Hospital, Saket

Sep 5, 2022

Liver Resection Surgery for Liver Cancer Treatment

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

Aug 30, 2022

Liver Transplant Surgery for Liver Tumour

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

Aug 28, 2022

Liver Transplant Surgery for Rare Liver Disease

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

Aug 12, 2022

Liver Transplant Surgery for Sclerosing Cholangitis

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

Aug 8, 2022

Gastrointestinal Stromal Tumour: Rare Condition

Treated by , Max Super Speciality Hospital, Dehradun

Jun 6, 2022

A Newly Born Baby with Rare Disease of Liver | Biliary Atresia Treatment

Treated by , Max Super Speciality Hospital, Saket

May 1, 2018

Liver Transplant: What You Need To Know

Treated by Prof (Dr.) Subhash Gupta, Max Super Speciality Hospital, Saket

May 24, 2017

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Liver Transplant Surgery for Autoimmune Liver Disease | Patient Success Story

Treated by Prof (Dr.) Subhash Gupta , Max Super Speciality Hospital, Saket

View all

Liver Transplant and Biliary Sciences Blogs

Diabetes and Liver – All You Need to Know

Liver involvement in patients with diabetes is a common presentation. The spectrum of liver involvement varies from abnormal liver enzymes to chronic liver disease and even liver failure. A healthy liver helps keep blood glucose within the normal range.

Dr. Sanjiv Saigal In Liver Transplant and Biliary Sciences

Marching Towards Healthy Liver - Symptoms of Liver Damage that You Should Not Ignore!

The liver is an amazing organ that performs over 500 vital functions. Some of its main functions include synthesis of proteins, storage of vitamins and minerals, secretion of bile, and detoxification of drugs and toxins that enter our body.

Dr. Sanjiv Saigal In Liver Transplant and Biliary Sciences

The liver is one of the vital organs in the human body

The liver is one of the vital organs in the human body. Unlike other organs in the body, the liver has a huge reserve, and physical signs and symptoms of liver disease arise only when most of the liver gets damaged.The common symptoms of liver disease are jaundice (yellow colour of eyes), loss of appetite/aversion to food, feeling of weakness and lethargy, abnormal bleeding occurring after minor trauma.

Prof (Dr.) Subhash Gupta In Liver Transplant and Biliary Sciences

Recipient Turns Donor

A liver that has been transplanted before would have suffered the rejection process. This particular liver which had been transplanted only 3 weeks ago, would not have reached a tolerogenic state as happens normally after transplantation. Therefore if transplanted in another recipient, potentially the rejection process would be more severe.

Prof (Dr.) Subhash Gupta In Liver Transplant and Biliary Sciences

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